CR3 (complement receptor 3) is a heterodimeric protein consisting of α (CD11b) and β (CD18) transmembrane glycoproteins. CD11b is unique for CR3, while CD18 is shared by members of the β2 integrin family including LFA1, CR4, and αdβ2. CR3 is found on monocytes, macrophages, dendritic cells, neutrophils, eosinophils, NK cells, and on some T and B cells.

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