Planning a Synthesis

• Challenges: Synthetic traps, such as incompatibilities or competing functional groups, can pose challenges during the synthesis process. These issues may not be obvious when considering individual steps but become apparent when looking at the overall synthesis

Evaluation: After going through the entire sequence buy nitroethane of reactions, it is important to re-evaluate the synthesis to see if there is a better way to achieve the desired product. This reflective process may lead to the identification of a more efficient approach

Approach to Synthesis Problems

• Nature of Problems: Synthesis problems involve identifying a sequence of reactions to transform a given molecule into the desired product. These problems become more common as students learn a larger pool of reactions in organic chemistry

Feasible Routes: When tackling synthesis problems, it is essential to identify feasible synthetic routes and evaluate their advantages and potential challenges. For example, different routes may lead to the formation of different products, requiring consideration of separation processes

Organic Synthesis Problems

• Practice and Resources: Students and researchers often seek practice problems and resources for organic synthesis at various difficulty levels. These resources may include theoretical exercises for synthesizing compounds by selecting reactants and starting materials, as well as access to comprehensive practice problems and quizzes [[3, 5]].

Energy-Efficient Process Synthesis

• Complex Energy Supply Systems: In a broader context, the term "synthesis problem" can also refer to the challenge of finding energy-efficient processes for complex energy supply systems. This involves the identification of process alternatives and the selection of the best alternative based on energy consumption